Defining Adverse, Non-adverse and Adaptive Responses in Safety/Risk Assessment
The judgment on the adverse nature of an observation in a non-clinical toxicology study is subject to discussion, challenge, and reinterpretation.
Carcinogenesis – World Toxicologic Pathology Congress
This carcinogenesis lecture created as part of a day course dealing with pathology for non-pathologists. Basic concepts are presented with pathology examples
The Legacy of the F344 Rat at the National Toxicology Program
This lecture is based on a 2016 publication in Critical Reviews in Toxicology (Vol 46:641-675) & also includes kidney and forestomach tumors in addition to mononuclear cell leukemia, Leydig cell tumors, and tunica vaginalis mesothelioma.
INHAND Non-Neoplastic Hepatobiliary Lesions
Material presented covers non-neoplastic rat and mouse lesions that are part of the INHAND nomenclature effort plus additional examples of liver tissue artifacts.