Robert Maronpot

About Robert Maronpot

Dr. Maronpot received his doctorate of veterinary medicine in 1965 from Michigan State University, an MS in nutritional pathology from Michigan State University in 1966, and an MPH from Harvard University in 1972. He is a diplomate of the American College of Veterinary Pathologists as well as the American Board of Toxicology and has worked more than forty years in experimental pathology, with an emphasis on animal models of carcinogenesis.

Synthetic and Natural Food Colorants

2020-05-21T17:28:39+00:00

There is increasing contemporary appeal and interest in natural versus synthetic food and beverage colorants based on increasing health awareness and global demand for chemical-free food products. There are many commonalities in defining and regulating food colorants among countries and specifics are provided for the United States, the European Union, and Japan. Overall [...]

Synthetic and Natural Food Colorants2020-05-21T17:28:39+00:00

Safety Assessment Testing Requirements for Food Color Additives

2020-05-21T17:25:50+00:00

Safety assessment of food colorants are fundamentally similar in Japan, Europe, and the United States and involve large amounts of data for new colorants and active monitoring of existing approved colorants. Testing requirement are similar for artificial and natural food colorants and include assays for genetic damage and use of animal toxicity studies [...]

Safety Assessment Testing Requirements for Food Color Additives2020-05-21T17:25:50+00:00

The Pathology of Selected Dietary Herbal Medicines as Observed in the National Toxicology Program Studies

2020-05-21T17:11:28+00:00

The popularity of herbal medicines is growing steadily all over the world, and a large number of people are using these products for self-medication. Although these medicines are being widely used, and the number of available products is increasing exponentially, most of these compounds have not been properly evaluated for potential toxic or [...]

The Pathology of Selected Dietary Herbal Medicines as Observed in the National Toxicology Program Studies2020-05-21T17:11:28+00:00

Food Color Additives

2020-05-21T17:03:45+00:00

This issue of the Foods and Food Ingredients of Japan includes a special section of papers that focus on synthetic and natural food additive colorants with presentation of governmental regulatory procedures in the U.S., Europe and Japan in bringing food colorants to the marketplace. While the food colorant marketplace is still dominated by [...]

Food Color Additives2020-05-21T17:03:45+00:00

Contemporary activities of Toxicologic Pathology Societies

2020-04-26T17:39:18+00:00

Educational activities and training opportunities in toxicologic pathology are major goals of 9 formally established Toxicologic Pathology Societies and the International Academy of Toxicologic Pathology. Some Toxicologic Pathology Societies have examination-based certification programs while others accept certification or registration by veterinary pathology organizations including the American College of Veterinary Pathologists, the European College [...]

Contemporary activities of Toxicologic Pathology Societies2020-04-26T17:39:18+00:00

Contemporary Activities of Toxicologic Pathology Societies (SAGE)

2020-04-29T15:48:29+00:00

Abstract: Educational activities and training opportunities in toxicologic pathology are major goals of 9 formally established Toxicologic Pathology Societies and the International Academy of Toxicologic Pathology. Some Toxicologic Pathology Societies have examination-based certification programs while others accept certification or registration by veterinary pathology organizations including the American College of Veterinary Pathologists, the European [...]

Contemporary Activities of Toxicologic Pathology Societies (SAGE)2020-04-29T15:48:29+00:00

Lack of preventive effect of maternal exposure to α-glycosyl isoquercitrin and α-lipoic acid on developmental hypothyroidism-induced aberrations of hippocampal neurogenesis in rat offspring

2020-04-21T18:00:35+00:00

Hypothyroidism during the developmental stage induces disruption of hippocampal neurogenesis in later life, as well as inducing oxidative stress in the brain. The present study investigated the preventive effect of co-exposure to an antioxidant on disruptive neurogenesis induced by developmental exposure to anti-thyroid agent in rats. For this purpose, we used two antioxidants, [...]

Lack of preventive effect of maternal exposure to α-glycosyl isoquercitrin and α-lipoic acid on developmental hypothyroidism-induced aberrations of hippocampal neurogenesis in rat offspring2020-04-21T18:00:35+00:00

Pathology of the Liver and Gallbladder

2020-04-29T15:41:10+00:00

Abstract: The liver is a major metabolic organ, and the first site of contact of xenobiotics follows oral ingestion or administration. The primary functional unit of the liver is the hepatic lobule. Gradients for metabolizing enzyme and oxygen tension in the hepatic lobule determine toxification and detoxification of ingested xenobiotics with immediately toxic [...]

Pathology of the Liver and Gallbladder2020-04-29T15:41:10+00:00

Ten-day and four-week toxicity and toxicokinetics studies of alpha-glycosyl isoquercitrin in juvenile Göttingen minipigs

2020-04-24T17:09:04+00:00

Background: Alpha-glycosyl isoquercitrin (AGIQ) is widely used as an anti-oxidative food additive in many products. Nevertheless, information on its safety and toxicity is still very limited. A 90-day toxicity study in rats and comprehensive genotoxic studies have proven AGIQ to be safe. Aim: The goal of this study was to assess the safety [...]

Ten-day and four-week toxicity and toxicokinetics studies of alpha-glycosyl isoquercitrin in juvenile Göttingen minipigs2020-04-24T17:09:04+00:00

Ameliorating effect of postweaning exposure to antioxidant on disruption of hippocampal neurogenesis induced by developmental hypothyroidism in rats

2020-04-26T17:11:18+00:00

Developmental hypothyroidism as a model of autism spectrum disorders disrupts hippocampal neurogenesis through the adult stage. The present study investigated the ameliorating effect of postweaning exposure to antioxidant on the hypothyroidism-induced disruptive neurogenesis. Mated female Sprague-Dawley rats were treated with 0 or 10 ppm 6-propyl-2-thiouracil (PTU) as an anti-thyroid agent in drinking water [...]

Ameliorating effect of postweaning exposure to antioxidant on disruption of hippocampal neurogenesis induced by developmental hypothyroidism in rats2020-04-26T17:11:18+00:00