Safety assessment of food colorants are fundamentally similar in Japan, Europe, and the United States and involve large amounts of data for new colorants and active monitoring of existing approved colorants. Testing requirement are similar for artificial and natural food colorants and include assays for genetic damage and use of animal toxicity studies as surrogates for human exposures. All studies are currently conducted in compliance with internationally recognized Good Laboratory Practices (GLP) with study design, conduct and evaluation carried out by trained and certified scientific experts in accordance with country-specific and international published safety assessment guidelines.
